Fabrication of Hydroxyapatite/Cotton Nanofiber Scaffolds for Biomedical Application

Xiu-fang ZHANG, Ying-ying ZHENG, Jia-qi PAN, Peng CHEN, Chao-rong LI

Abstract


Electro spun nature fibers have been investigated as scaffolding materials for bone tissue engineering. Our study was to develop a novel composite cotton nanofiber scaffolds by attaching hydroxyapatite (HA) to cotton nanofibers (CF) using an adhesive material (the mussel-inspired protein polydopamine) as a superglue. Result show that the sheet-like HA was successfully deposited on the CF in short time (30h) and 37℃ (human body temperature). The diameter of HA functionalized CF was 1 μm, and the surface become rougher. These results demonstrate this HA/CF scaffold is promising for repair bone defects.

Keywords


Electro spun; Cotton nanofiber (CF) ; Hydroxyapatite(HA); Polydopamine


DOI
10.12783/dtmse/msce2016/10479

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