Design and Simulation of Integrated Sensor for Measuring the Extracellular Potential and Cell Impedance

Abstract

Analysis of the cell electrophysiology is important for biomedical study. To monitor the cell electrophysiology from different sides, this article produced to design an integrated sensor for measuring the extracellular potential and cell impedance synchronously. To design a fit sensor for acquiring accurate and effective experiment data, infinite element simulation of electric field of electrode was used to ensure the electrode form, size and distribution. Integrated sensor for measuring the extracellular potential and cell impedance can obtain multiple electrophysiological parameters synchronously and it is very important in drug analysis, drug effect evaluation, environmental monitoring, food safety supervision, and other biomedical domain.